The events of the game begin during Thanksgiving Day 1991, two years after the events of Ghostbusters II. The Ghostbusters, now official city contractors, are training a new recruit, whom Dr. Venkman insists they simply call “Rookie”, so they don’t get too attached, in case something should happen to the new hire while testing out experimental equipment.

Metal Slug 1-6 and X are included in the release, and the games have not been altered in any way. This is the same with the characters and abilities, which have all been kept the same.