Toni Cipriani, having been forced into living abroad after killing a made man on the orders of Salvatore Leone, decides to return to Liberty City. Upon arrival Toni is greeted by Salvatore and a member of the Leone family, Vincenzo “Lucky Vinnie” Cilli, who rose to prominence during Toni’s absence.

Vic Vance is a corporal in the U.S Army. He is a man who came from a poor family, with his brother suffering from asthma and another lazy brother, and he is trying to make money for his dysfunctional family. He just arrived in Vice City in 1984 and he is now stationed at Fort Baxter.